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Anestesiología Mexicana en Internet (AMI) inició en marzo de 1997. Página electrónica oficial de Anestesiólogos Mexicanos en Internet, A.C. Asociación organizadora del Congreso Virtual Mexicano de Anestesiología (www.congresodeanestesiologia.com) |
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Luis Federico Higgins Guerra
Universidad Nacional Autónoma de México. Anestesiología en Instituto Nacional de Neurología y Neurocirugía 'Dr. Manuel Velasco Suárez. Subespecialidad en Neuroanestesiología (INNN). Autor del libro 'Anestesia Obstétrica' (2008, 2a edición, El Manual Moderno).
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03 de Septiembre, 2008
· Farmacologia |
¿Debe abandonarse el uso de la succinilcolina? |
Succinylcholine, despite its many side effects, has been used for more than 50 yr as the standard neuromuscular blocking drug (NMBD) to facilitate tracheal intubation. Its popularity reflects the lack of viable alternatives with rapid onset and short duration. The purpose of this article is to review the important unwanted effects of succinylcholine and to describe the drugs and techniques that modified the action of existing nondepolarizing NMBDs to resemble succinylcholine. The new aminosteroid muscle relaxant, rapacuronium, will be introduced as the first nondepolarizing muscle relaxant with both rapid onset and short duration.
For elective procedures, succinylcholine should be avoided, particularly in infants and children. Rapacuronium appears to have ideal properties when a drug is required only either to facilitate tracheal intubation or for short surgical procedures. Although rapacuronium has been approved by the Food and Drug Administration for use for the induction of anesthesia and rapid sequence endotracheal intubation, further clinical experience is necessary before rapacuronium can be confirmed to provide ideal intubating conditions as a component of rapid sequence induction of anesthesia techniques to avoid the risk of aspiration of gastric contents in patients of various ages with so-called full stomachs.Artículo: Bajar el artículo completo [clic aquí] |
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publicado por
higgins a las 15:54 · Sin comentarios
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